WASHINGTON: Eating soy could pose risks to some women who begin
consuming it as adults by making breast cancer tumours resistant to treatment,
US researchers said on Monday.
A study on lab rats showed that those who were fed a soy compound all
their lives responded well to a popular breast cancer drug, tamoxifen, but
those who began eating it as adults, and after they developed breast cancer,
grew resistant.
The research suggests a possible reason why tamoxifen stops working and
allows tumours to grow again in some women, said scientists from Georgetown
University who presented their findings at a medical conference in Chicago.
"These results suggest that Western women who started soy intake
as adults, should stop if diagnosed with breast cancer," said senior
author Leena Hilakivi-Clarke, professor of oncology at Georgetown.
Soy contains isoflavones that mimic the estrogen produced in the body,
only at lower levels, and is considered a healthy protein source found in foods
like tofu, miso, soy beans and soy milk.
Its potential benefits against breast cancer are often linked to the
lower rates of hormone receptor positive types of breast cancer seen in Asian
women who live in parts of the world where soy consumption is common.
Since tamoxifen is typically given to breast cancer patients with
estrogen receptor and/or progesterone receptor positive types of tumours, the
finding suggests that late-life adoption of a soy diet may have rendered the
drug impotent.
The study was presented at the American Association for Cancer Research
(AACR) Annual Meeting.
- AFP/al
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